Biology 2.0 research at the intersection of single-cell transcriptomics, artificial intelligence, and reproducible computational biology
Dynamic analysis of cellular states, trajectories, and heterogeneity
Multi-method validation, quantitative state indices, and reproducible workflows
Computational frameworks for cancer biology and treatment response
Awarded under the FENIX 2025 call of PRACE, this project develops a robust and reproducible framework for analysing dynamic cellular states in human single-cell transcriptomic data.
The workflow combines RNA velocity with quantitative cell-state indices and a multi-method robustness panel. Fifteen complementary inference methods will be compared across non-pathological reference atlases and cancer datasets, including therapy resistance.
The project is supported by the GAIA Cloud platform at CINECA, Italy, with 96 vCPUs, 1.5 TB of persistent storage, and one public IP address for 12 months. Project is active since 01. September 2026.

Published research rebuilt from its own data. Each paper becomes an interactive page where readers explore every result, compare conditions and test their own data against the published results. The same data is served to AI agents through MCP, so anyone can query the paper from their own assistant.
First paper: Živanović et al., Pharmaceutics 2023, with its complete real-time viability, flow cytometry, gene expression and model data. More papers, across methods and fields, will follow. Live since September 2026.
Every curve, cell-death state and gene from the paper, one click from its source figure.
An MCP server gives any assistant the same data, with every answer traced to its figure or table.
Drop your own instrument export and compare it with the published curves. The file never leaves your browser.
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